I had to do a 180 [degree turn] and start researching this

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When misfolded proteins accumulate in the ER wholesale steroids, however, the folding capacity of the ER may be exceeded. This triggers a cellular response pathway called the unfolded protein response, aimed at restoring homeostasis in the ER via transcription regulation and translational attenuation. We provide evidence that misfolding/misoxidation of the major histocompatability complex (MHC) class ….  Read More